Datatable Destroy() taking too much time.

In my application i'm loading huge data into data table. And in that datatable i want to search using some search filters. In that case, what i am doing is i'm destroying the previously loaded table and again loading data by search filters again.

Here the problem is because of huge data like 50k records its taking too much time to destroy data table, and some times page it self not responding.

So is there any other way to handle this ?