Headers not lining up

I am using datatables in an application and I am constantly battling the headers not lining up with the contents. I even have a page where it works on first load but a reload messes it up.

There have been many reports of people having the same issue.
I have tried using fnAdjustColumnsizing. I have tried autowidth as true and false.

What is the sure fire way of getting this to work consistently?
Surely there is a real issue here?

If you are seeing the same issue then please comment on this post.